Humulin N Cartridge
HUMULIN has been produced by recombinant DNA processes.
It differs from animal-source insulins because it is structurally identical to the insulin produced by your body’s pancreas and because of its unique manufacturing process.
HUMULIN N – NPH (insulin isophane, human biosynthetic, rDNA origin) has been modified so that it has a different duration of action than Regular insulin. The result is an intermediate-acting insulin with a slower onset of action than Regular insulin and a duration of activity between 16 to 18 hours.
HUMULIN N cartridges and HUMULIN N KwikPen (prefilled pens) are for subcutaneous (under the skin) injection only.
What the medication is used for:
HUMULIN N is an intermediate-acting insulin used to treat patients diagnosed with diabetes mellitus.
What it does:
Insulin is a hormone that decreases the amount of sugar in your blood and urine by increasing the uptake of sugar from your blood into various tissues, such as the liver, muscles, and fat.
To control your diabetes, your doctor has prescribed injections of insulin to keep your blood sugar at a nearly normal level and to keep your urine as free of sugar as possible.
When it should not be used:
HUMULIN N should not be used if you are allergic to this drug or any of the ingredients used to formulate this medication.
HUMULIN N should not be used during episodes of hypoglycemia (too little sugar in the blood).
HUMULIN N should not be given intravenously or used for treatment of diabetic coma.
HUMULIN N should be used only if your doctor has prescribed NPH insulin (insulin isophane). You should not attempt to add any insulin to this cartridge or KwikPen (prefilled pen).
If HUMULIN N and HUMULIN R mixtures are prescribed, the individual insulins should be mixed as instructed in the amounts recommended by your doctor or purchased as mixtures in the ratio recommended if available.
What the medicinal ingredient is:
HUMULIN N contains insulin isophane, human biosynthetic.
What the nonmedicinal ingredients are:
Glycerol, m-cresol, water for injection, hydrochloric acid, sodium hydroxide, phenol, zinc oxide, protamine sulfate and
dibasic sodium phosphate.
What dosage forms it comes in:
HUMULIN N (NPH) is a sterile suspension containing insulin isophane, human biosynthetic (rDNA origin) for subcutaneous injection. It is available in:
– Cartridges, 3 mL
– KwikPens, 3 mL prefilled pen
HUMULIN N is also available in:
– Vials, 3 mL
– Vials, 10 mL
Other available HUMULIN products include HUMULIN R (Regular) and HUMULIN 30/70 (mixture of 30% Regular
and 70% NPH). These types of insulin differ mainly in the time they require to take effect and in the length of time their action lasts. Your doctor has prescribed the type of insulin that he/she believes is best for you. Do not use any other insulin except on your doctor’s advice and direction.
When you receive your insulin from the pharmacy, always check to see that:
1. The name HUMULIN appears on the carton and cartridge or KwikPen (prefilled pen) label and is followed by the proper letter designation and name for the insulin formulation: N-NPH.
2. The carton and cartridge or KwikPen label is correct for your type of insulin.
3. The human insulin is of rDNA origin.
4. The insulin strength is U-100.
5. The expiration date on the package will allow you to use the insulin before that date.